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An imaging test. One group of patients with chest pain received standard stress testing; the other received standard stress testing plus a coronary CT scan (CCTA). Here is the 5-year survival curves for the composite endpoint of CV death and MI: How can a diagnostic test lead to this much benefit? Not a drug.
They carry out doctor’s orders, check up on patients throughout the day, and make sure providers have accurate information when looking at the patient’s chart. Nurses may need to refresh their memory of this knowledge every few years to make sure they have the latest and most up to date information. 34 12 votes, 1.9
In the years that followed, I learned of efforts to remove racial identifiers from medical textbooks and test questions. Race is a therefore terrible diagnostic test. We define diagnostic tests as tools that distinguish two populations, in medicine, diseased and healthy. We do this with BRCA testing.
If patient data tripped the alert, an EMR pop-up message would appear for nurses and physicians. These alerts were backed up with training and monitoring to encourage real action. Process measures suggested that doctors and nurses responded to the alerts with increased testing of lactate levels and fluid resuscitation.
As a skeptic of this imaging test, I saw the headline and thought: finally, we will learn whether patients who have their chest radiated have better outcomes. Same with imaging tests. Trial Results After 3 years of follow-up, the CAC score-informed group showed significantly greater reductions LDL-C levels compared to usual care.
A Google search brings up news releases from Vertex , and news coverage—which are essentially the same and lacking links to the evidence. The differences (from baseline) at each time are summed and weighted to come up the score. Last week the FDA approved a novel non-opioid pain medication. This was much more difficult to find.
It’s been a few years since I first heard about the Galleri test produced by the Menlo Park startup Grail. Galleri is a blood-based screening test for cancer. For a couple of reasons, I didn’t work very hard to learn about the Galleri test. Second, I was worried that this test might have real promise.
What there was -- courtesy of colleagues from across the country – were cases illustrating needless excess, careless follow-up, poor commitment to clinical care, and the devaluation of primary care that undermines our entire system. They also repeated all the tests that the community hospital had done.
We so desperately need RCT data for our screening tests. Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial I’ve come out pretty strongly against GDMT. It also shows us how hard it is to up-titrate GDMT.
The USPSTF claims "screening interventions" decrease the prevalence of depression at six-month follow-up by an odds ratio of 0.60. This number is surprising when we consider the following: A meta-analysis of six RCTs found the benefit of SSRIs, compared to placebo, to be small and statistically insignificant at six months.
The medical college admission test contains many irrelevant questions that have nothing to do with being a doctor. There was a follow-up component to the biochemistry question, and it too was a logic puzzle, however, unfortunately it was incorrect. Next up… residency. I recently did some sample MCAT questions.
I even have a talk, “keeping up on the literature.” All had urea breath tests for Helicobacter pylori , the bacteria that causes most peptic ulcer disease and is closely associated with gastric cancer. People that tested negative were followed. Those who tested positive received either curative H.
Ordering diagnostic tests is a standard procedure for physicians; yet if the test results aren’t reviewed and acted upon, what was the point of ordering the test? However, Dr P, who had an extremely high caseload at the medical center, failed to followup on this finding. Some followup on results.
Trials select their patients, test the drugs in run-in periods and use research coordinators to help patients navigate complex health systems. Actual cardiologists performed these visits, which included up-titration of meds, but, also, as Adam correctly notes, patients had MD-level assessments. But trials are best case scenarios.
He acknowledges that we have little to no data that our currently accepted cancer screening tests reduce all cause mortality. ” Going further, Dr. Attia argues that our studies of screening tests do a poor job of finding the benefit of screening. There is a very small chance this test will save your life.
In a followup post , Adam Cifu, my friend and colleague, took me to task. ” Photo via instagram (you can follow me there). Those are the loose, plastic ones that end up in the ocean, strangling turtles and other sea creatures, after being used for armed robberies or college protests. A reduction of 3%.
“It just doesn’t follow the science. ” Now that the state mask mandate is null and void, it’s up to each facility to implement its own mask requirements. Chin-Hong said he expects many hospitals will still require masks for all patients and staff but that requiring every facility to mask up no longer makes sense.
They spend money on test prep courses and needle their teachers into inflating grades. They were dedicated, followed directions, worked hard, were skilled at the “customer service” side of medicine, and were mature enough to know that medicine was for them.
Sure, sometimes we ask you to do a fit test. The providers who make my job harder and make me feel useless insinuate that we administrators follow rules blindly, as if someone like me were part of a herd of sheep and not an adult with a master’s degree. We know more about hospital governance than most doctors do.
The biotech firm known as Grail made headlines earlier this year thanks to its signature Galleri blood tests, which can detect up to 50 different kinds of cancer early on to improve patient outcomes. The tests were hailed as the “first of its kind” when it hit the market in 2023. It’s that they simply didn’t exist.
Providers are typically paid for each test and procedure they perform, which can lead to a conflict of interest, especially when patients have to foot the bill. New studies reveal just how widespread medically unnecessary care can be, forcing patients to pay for procedures and tests they may not need. The findings were astonishing.
Dereck Paul is the co-founder of Glass Health, a start-up in San Francisco that offers artificial intelligence chatbot services to doctors looking to ease the burden of routine processes, such as patient documentation. “So, what tests they would order and what treatments they would order.”
The idea was that interventions could then be tested in the high-risk groups. I admit that I do not follow the Medical AI literature closely. I imagined that the tool was picking up more than just vascular calcifications and heart size. This was long ago enough that I was awed by the potential. 3 Is a CXR datum or data?
Don’t get hung up on the specific medical problem. The medical question comes up pretty often: What to do with moderate anemia (low red blood cell counts) in a patient recovering from a heart attack (myocardial infarction = MI)? (We The MINT trial tested these two strategies. No drug companies. No devices. with CI to 0.99-1.7
And it puts to the test an everyday practice in US cardiology. The second area of uncertainty was the question of going right to the cath lab for angiography after a positive stress test. It was a conservative vs early invasive approach to ischemia test. The Trial Patients had to have a positive stress test.
We read about diseases and their associated diagnostic tests and treatments. Clinical findings and blood tests hint at the diagnosis, but the only truly confirmatory test is a biopsy of the temporal artery – a small procedure but a procedure all the same. Diagnostic tests give you more than just a diagnosis.
Yet, like most unexpected clinical changes in my career, I ended up learning unexpected truths. A few years before, on a routine visit, they drew a a large battery of blood tests, and recommended colonoscopy. Because this was a non-invasive test (a CT scan), he went ahead with it. One man taught me about lung cancer screening.
For example, Bergman reports a 2002 study in which ventilated premature babies were placed to sleep on either their tummies or backs, and the following states were measured: quiet sleep, active sleep (which is less restorative than quiet sleep), crying time, number of stress responses (startle, tremor, and twitch), and oxygen saturation.
I’ve been following the general conversations and have been particularly interested in AI’s potential to improve diagnostic performance. The test characteristics of most data from the history is poor. I started with a steroid two years ago, but the pain was too severe and I ended up with an injection in my back.
When you call a patient to followup and they don’t pick up. When you’re just trying to do your job, but the universe decides to test your patience with a ripped glove. When you’re just trying to enjoy your sandwich, but your co-worker won’t stop talking.
It had long follow-up and enrolled patients who had established heart disease. The clinical equivalent of their approach was similar to stress testing for finding coronary stenoses. It was as if they had found a positive stress test in a patient with low-risk for heart disease.
Commentary The authors conclude that “protocol-directed active surveillance offers a clear set of expectations for patients and clinicians to follow.” This cohort was primarily made up of insured, educated, and non-Hispanic white patients. ” This is perhaps too strong a conclusion given this study’s design.
For calcium deposits in breast arteries to be important, we would need to know that some action based on this finding, whether it be further diagnostic testing, lifestyle modification, or medical therapy, actually benefits a woman. This finding suggests an increased risk of coronary artery disease; clinical followup recommended.”
I told him I would send a test to verify the diagnosis but that we would start treatment immediately. I told him that when the test came back positive, he would need to tell Grace so that she too could be tested and treated if necessary. Give me the test and the antibiotics. “Yeah, I am a total dog.
It can be caused by failure of the testes to produce testosterone or by a problem higher up in the “pituitary-hypothalamic axis.” If you understand the normal distribution, and thus how we define what is a normal blood test result, and are, or know, a man over 45, you realize this is an ENORMOUS market.
Then someone discovered that the largest living thing in the world was actually the 106 acre, 47 thousand tree Pando aspen grove in central Utah, which genetic testing revealed to be a single organism. United channeled almost $52 billion of that cash into buying health-related businesses, nearly all of which end up housed inside Optum.
They were healthy and needed to deal with a single issue or felt like it was time for a “check-up.” ” He left without making a followup appointment and I never saw him again. When I think back on PW and our interactions around his insomnia, I end up shaking my head. “I am truly sorry to hear that.
She estimates that this prompt saves her up to two hours per week , and sometimes even more when demand is high. She estimates that this prompt saves her about an hour daily , adding up to 7 hours weekly and nearly 28 hours monthly. Follow-up in three months with repeat labs. GPT helps me generate them efficiently."
A place where a learner can go to look up the seminal trials that established modern day cardiology practice. This trial tested the use of early IV beta-blocker (atenolol) in patients with MI. Instead of starting oral beta-blocker many days after MI in BHAT, ISIS1 tested immediate use of IV beta-blocker.
Even though my practice is made up of about 750, overwhelmingly older people, mostly with chronic medical conditions, I only attend to the death of a patient a few times a month. There have been previous admissions after which the patient did not make it to follow-up appointments. Acceptance followed and waxed and waned.
NHANES is one of the many registries that measure health parameters in adults and then follow them for years. In this study, among 10,000 adults, nearly 2000 had completed hearing tests and had hearing loss. The effect held up even when the researchers accounted for differences such as age, ethnicity, education, and medical history.
I asked Anupam Jena if he could run the Medicare analysis on docs with R01s vs those without, but he felt it would be limited by thin data, and also pointed out that what they lost in clinical skills, they might make up for in intelligence. Most have given up the lab, and are largely clinicians or work in other sectors.
How large a number needed to screen is too large for a test to be acceptable? If we are to reach agreement on the benefit of cancer screening, thus enabling guideline committees to speak with one voice, we must agree on what constitutes an effective screening test and on how much we, as a nation, are willing to pay for it.
The device becomes a screening test or provides information to “promote wellness.” Perhaps the most well-known example happened when the nature of primary hyperparathyroidism changed with the advent of automated multi-channel chemistry tests. ” My ears prick up. “Yes, it often peaks up to 140 mg/dL (7.8
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