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Sepsis Screening Decreases Mortality. Well, not really.

Sensible Medicine

If patient data tripped the alert, an EMR pop-up message would appear for nurses and physicians. These alerts were backed up with training and monitoring to encourage real action. Reading who uses these five hospitals in Saudi Arabia, it seems like a population that would be easy to follow. 3 I’ve written editorials.

Hospital 243
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Duration of Trials vs Duration of Therapy

Sensible Medicine

Let’s ignore those and assume that intensive therapy is better over the 3+ years of follow-up. The average follow-up time of these 58 year-old patients was 5 years. years the trial was stopped prematurely because the intensive arm led to lower rates of major adverse cardiac outcomes.

Follow-Up 239
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Mental Health Crisis in Miscarriage–an Unrepresented Patient Population

The Healthcare Blog

Two weeks after my emergency room discharge, I continued to live life as if nothing happened, returning to work without any healthcare follow-up to address my emotional burden. At only nine weeks gestation I had not seen my OB physician yet, but I was able to follow up in the office to talk about my next steps.

Follow-Up 107
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A review of the newly approved novel non-opioid pain reliever suzetrigine (Journavx)

Sensible Medicine

A Google search brings up news releases from Vertex , and news coverage—which are essentially the same and lacking links to the evidence. The differences (from baseline) at each time are summed and weighted to come up the score. Last week the FDA approved a novel non-opioid pain medication. This was much more difficult to find.

Follow-Up 265
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What I Read This Week

Sensible Medicine

Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial I’ve come out pretty strongly against GDMT. It shows a benefit of close follow-up in a heart failure clinic. (It The results were impressive.

Follow-Up 284
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Universal Depression Screening Leads to Unnecessary Harm

Sensible Medicine

The USPSTF claims "screening interventions" decrease the prevalence of depression at six-month follow-up by an odds ratio of 0.60. This number is surprising when we consider the following: A meta-analysis of six RCTs found the benefit of SSRIs, compared to placebo, to be small and statistically insignificant at six months.

Follow-Up 360
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Friday Reflection 41: Sometimes I Just Need to Complain

Sensible Medicine

What there was -- courtesy of colleagues from across the country – were cases illustrating needless excess, careless follow-up, poor commitment to clinical care, and the devaluation of primary care that undermines our entire system. In the days following, there are questions, or test results, or complications.

Follow-Up 261