When Trials Find Implausible Results—The SCOT-HEART trial
Sensible Medicine
JANUARY 27, 2025
Here is the 5-year survival curves for the composite endpoint of CV death and MI: How can a diagnostic test lead to this much benefit? Foreknowledge of normal coronary anatomy could potentially bias the investigator to not pursue diagnostic testing (biomarkers or electrocardiogram), thereby amplifying the difference in Mis.
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